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BMC Complementary and Alternative Medicine

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Clinical research

Edited by Holger Cramer, Jianping Liu and Karen Pilkington

This section covers research reporting clinical applications of interventions or resources in the complementary medicine field, including the evaluation of the efficacy and safety of the therapies, clinical trials and systematic reviews/meta-analysis.

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  1. Content type: Research article

    Conventional therapy (CT) such as donepezil and memantine are well-known short-term treatments for the symptoms of Alzheimer’s disease (AD). The efficacy of them, however, drops below baseline level after 9 mo...

    Authors: Jing Shi, Jingnian Ni, Tao Lu, Xuekai Zhang, Mingqing Wei, Ting Li, Weiwei Liu, Yongyan Wang, Yuanyuan Shi and Jinzhou Tian

    Citation: BMC Complementary and Alternative Medicine 2017 17:533

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  2. Content type: Research article

    Chinese herbal medicine formula Yu ping feng san (YPFS) is commonly used for allergic rhinitis (AR). Previous review had summarized the effectiveness and safety of YPFS, however without any subgroup analysis perf...

    Authors: Qiulan Luo, Claire Shuiqing Zhang, Lihong Yang, Anthony Lin Zhang, Xinfeng Guo, Charlie Changli Xue and Chuanjian Lu

    Citation: BMC Complementary and Alternative Medicine 2017 17:485

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  3. Content type: Research article

    Joint and connective tissue integrity, comfort and function are paramount to optimal performance in exercise, recreational and occupational activities. The fruit of Terminalia chebula has been used extensively in...

    Authors: H. L. Lopez, S. M. Habowski, J. E. Sandrock, B. Raub, A. Kedia, E. J. Bruno and T. N. Ziegenfuss

    Citation: BMC Complementary and Alternative Medicine 2017 17:475

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  4. Content type: Study protocol

    Although various treatments for breast cancer related lymphedema exist, there is still a need for a more effective and convenient approach. Pilot studies and our clinical observations suggested that acupunctur...

    Authors: Huiru Zhu, Jinwan Li, Zheng Peng, Yujie Huang, Xiaolan Lv, Liuying Song, Gechen Zhou, Shengzhang Lin, Jifei Chen, Baoyu He, Fengxian Qin, Xumexiang Liu, Meiyu Dai, Yan Zou and Shengming Dai

    Citation: BMC Complementary and Alternative Medicine 2017 17:467

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  5. Content type: Research article

    The beneficial effects of traditional herbs of Crete, Greece for the treatment of upper respiratory tract infections have been reported in observational and laboratory studies. Following a published, double bl...

    Authors: Marilena Anastasaki, Antonios Bertsias, Stergios A. Pirintsos, Elias Castanas and Christos Lionis

    Citation: BMC Complementary and Alternative Medicine 2017 17:466

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  6. Content type: Research article

    Most of the current anti-fungal treatments are chemical-based, fungistatic, have low efficacy in the treatment of tinea and toxicity concerns, while onychomycosis remains recalcitrant to most antifungal therap...

    Authors: Manoj Parekh, Girisha Ramaiah, Prachi Pashilkar, Ranjani Ramanujam, Peter Johnston and Leodevico L. Ilag

    Citation: BMC Complementary and Alternative Medicine 2017 17:464

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  7. Content type: Research article

    Mistletoe extracts have anti-tumor properties and are approved for subcutaneous use in cancer patients. Data on Intravenous application are limited.

    Authors: Roman Huber, Dietrich Schlodder, Carola Effertz, Sabine Rieger and Wilfried Tröger

    Citation: BMC Complementary and Alternative Medicine 2017 17:465

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  8. Content type: Research article

    Impaired glucose regulation (IGR) patients have increased risk of type 2 diabetes mellitus (T2DM). Identifying relevant risk factors in IGR subjects could facilitate early detection and prevention of IGR progr...

    Authors: Hong You, Tong Zhang, Wen Feng and Yun Gai

    Citation: BMC Complementary and Alternative Medicine 2017 17:459

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  9. Content type: Research article

    The objective of the current study was to assess the in vitro antiplasmodial activities of leaf, bark, flower, and the root of Pongamia pinnata against chloroquine-sensitive Plasmodium falciparum (3D7 strain), cy...

    Authors: P.V.V. Satish and K. Sunita

    Citation: BMC Complementary and Alternative Medicine 2017 17:458

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  10. Content type: Research article

    Approximately 11% of the German population are convinced that certain moon phases and moon signs may impact their health and the onset and clinical course of diseases. Before elective surgery, a considerable n...

    Authors: A. Kleespies, M. Mikhailov, P. N. Khalil, S. Pratschke, A. Khandoga, M. Stangl, W. D. Illner, M. K. Angele, K. W. Jauch, M. Guba, J. Werner and M. Rentsch

    Citation: BMC Complementary and Alternative Medicine 2017 17:440

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    The Correction to this article has been published in BMC Complementary and Alternative Medicine 2017 17:478

  11. Content type: Research article

    Indigo naturalis is a Traditional Chinese Medicine (TCM) ingredient long-recognized as a therapy for several inflammatory conditions, including psoriasis. However, its mechanism is unk...

    Authors: Hui-Man Cheng, Yang-Chang Wu, Qingmin Wang, Michael Song, Jackson Wu, Dion Chen, Katherine Li, Eric Wadman, Shung-Te Kao, Tsai-Chung Li, Francisco Leon, Karen Hayden, Carrie Brodmerkel and C. Chris Huang

    Citation: BMC Complementary and Alternative Medicine 2017 17:439

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  12. Content type: Research article

    Primary dysmenorrhoea (PD), defined as painful menses in women with normal pelvic anatomy, is one of the most common gynaecological syndromes. Acupoint-stimulation could potentially be an effective interventio...

    Authors: Yang Xu, Wenli Zhao, Te Li, Huaien Bu, Zhimei Zhao, Ye Zhao and Shilin Song

    Citation: BMC Complementary and Alternative Medicine 2017 17:436

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  13. Content type: Research article

    Feverfew (Tanacetum parthenium L.), magnesium and coenzyme Q10 are frequently used for migraine prophylaxis. Supplementation with a fixed combination of these three agents (Antemig®, PiLeJe) was investigated in a...

    Authors: Angèle Guilbot, Marie Bangratz, Samira Ait Abdellah and Christian Lucas

    Citation: BMC Complementary and Alternative Medicine 2017 17:433

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  14. Content type: Research article

    Use of complementary and alternative medicine (CAM) is widespread among different patient populations despite the availability of evidence-based conventional medicine and lack of supporting evidence for the cl...

    Authors: Mandreker Bahall

    Citation: BMC Complementary and Alternative Medicine 2017 17:422

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  15. Content type: Research article

    To achieve effective antiretroviral therapy (ART) outcomes, adherence to an antiretroviral regimen and a good immunometabolic response are essential. Food insecurity can act as a real barrier to adherence to b...

    Authors: Koy Tshingani, Philippe Donnen, Henri Mukumbi, Pierre Duez and Michèle Dramaix-Wilmet

    Citation: BMC Complementary and Alternative Medicine 2017 17:420

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  16. Content type: Research article

    Extracts from perna canaliculus, the Green Lipped Mussel (GLM) are widely used as a complimentary therapy by patients with osteoarthritis (OA). The current study investigated the potential of a novel GLM formulat...

    Authors: Simon Stebbings, Andrew Gray, Anthony G. Schneiders and Andrew Sansom

    Citation: BMC Complementary and Alternative Medicine 2017 17:416

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  17. Content type: Research article

    The purpose of the present study was to examine the body composition of So-Yang type males according to Sasang constitutional medicine, which is popular in Korea. Different Sasang constitutional types are asso...

    Authors: Jiwon Yoon, Jiho Nam, Chae Hun Leem and Jong Yeol Kim

    Citation: BMC Complementary and Alternative Medicine 2017 17:417

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  18. Content type: Study protocol

    Primary dysmenorrhea (PD) is one of the most common health complaints all over the world, specifically among young females. Acupuncture has been employed to relieve the pain-based symptoms and to avoid the sid...

    Authors: Yingfan Chen, Sinan Tian, Jing Tian and Shi Shu

    Citation: BMC Complementary and Alternative Medicine 2017 17:421

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  19. Content type: Research article

    Shinrin-yoku (experiencing the forest atmosphere or forest bathing) has received increasing attention from the perspective of preventive medicine in recent years. Some studies have rep...

    Authors: Yuki Ideno, Kunihiko Hayashi, Yukina Abe, Kayo Ueda, Hiroyasu Iso, Mitsuhiko Noda, Jung-Su Lee and Shosuke Suzuki

    Citation: BMC Complementary and Alternative Medicine 2017 17:409

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  20. Content type: Study protocol

    Colorectal cancer imposes threats to patients’ well-being. Although most physical symptoms can be managed by medication, psychosocial stressors may complicate survival and hamper quality of life. Mindfulness a...

    Authors: Rainbow T. H. Ho, Adrian H. Y. Wan, Jessie S. M. Chan, S. M. Ng, K. F. Chung and Cecilia L. W. Chan

    Citation: BMC Complementary and Alternative Medicine 2017 17:390

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