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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Inhibition of airway remodeling and inflammatory response by Icariin in asthma

Fig. 4

ICA inhibited the release of IL-13 and ET-1 in BALF and blood serum. Wild-type BALB/c female mice received vehicle or 0.2 ml sensitizing mixture (100 μg OVA and 1 mg aluminum hydroxide gel in sterile saline solution) on days 1 and 8. Then, mice were inhaled 1% OVA once a day for 0.5 h on days 16–43, and mice received vehicle or ICA (25, 50, or 100 mg/kg) or 1 mg/kg DXM 1 h before OVA inhalation. a, b ELISA measurement of IL-13 in BALF and in blood serum. c, d ELISA measurement of ET-1 in BALF and in blood serum. Data are shown as mean ± SEM (n = 10) . *P < 0.05 versus control group and #P < 0.05 versus OVA group

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