Fig. 3

Effect of repeated addition of BPJ plus atosiban (15 μL and 4.3 μL of 375 μg/mL, respectively) and of BPJ plus nifedipine (15 μL and 5 μL of 3.7 μg/mL, respectively) on human myometrial contractility in vitro. All test substances were repeatedly added to the myograph chamber. The line chart shows the AUC (a), the amplitude (b), and the frequency (c). Data were obtained with 5 different biopsies (n = 5) and are expressed as percentage of initial. The repeated addition of BPJ was performed for comparison; Krebs solution (5 μL) was used as control. *p < 0.05