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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Inhibitory effects of berberine on proinflammatory M1 macrophage polarization through interfering with the interaction between TLR4 and MyD88

Fig. 4

Morphological changes after high-dose LPS intervention (a) and the effects of BBR on LPS-induced TNF-α secretion (b-c) in Raw264.7 cells at different times. N, control group; LL, 0.1 μM LPS group; LL-B, 0.1 μM LPS + BBR group; LL-M, 0.1 μM LPS + Metformin group; LH, 0.1 mM LPS group; LH-B, 0.1 mM LPS + BBR group; LH-M, 0.1 μM LPS + Metformin group. Compared with control group, ###P < 0.001; Compared with LL or LH group, *P < 0.05, **P < 0.01, ***P < 0.001

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