Fig. 1

Effect of JPYW on the lifespan of C. elegans N2 worms under normal conditions. a The worms were treated with JPYW beginning at the larval stage. The curves show the percentages of surviving worms on different days after treatment with a vehicle control (1% DMSO) or 150 μg/ml JPYW. JPYW did not significantly prolong the lifespan of wild-type worms, but it caused a positive trend in the number of surviving aged worms (n = 50). b The aged worms were exposed to JPYW beginning on the 7th day of adulthood. The curves show the percentages of surviving worms on different days after treatment with a vehicle control (1% DMSO) or 150 μg/ml JPYW. JPYW significantly prolonged the lifespan of aged wild-type worms; n = 50–51, P < 0.05