Isolation of bioactive compounds from Bergenia ciliata (haw.) Sternb rhizome and their antioxidant and anticholinesterase activities

Table 6 Percent AChE and BChE inhibition potential of pyrogallol, morin and rutin isolated from Bergenia ciliata rhizome

Samples	Concentrations (μg/mL)	AChE percent inhibition (mean ± S.E.M)	AChE IC₅₀ (μg/mL)	BChE percent inhibition (mean ± S.E.M)	BChE IC₅₀ (μg/mL)
Pyrogallol	1000	94.35 ± 0.72 ^ns		92.02 ± 1.89 ^ns
	500	87.40 ± 1.51 ^ns		80.35 ± 0.30 *
	250	80.12 ± 0.62 ^ns	28	71.18 ± 1.38 ^ns	70
	125	66.24 ± 2.14 ^ns		58.28 ± 0.93 ^ns
Morin	1000	85.51 ± 3.19***		80.46 ± 0.76***
	500	77.23 ± 0.91***		68.44 ± 2.22***
	250	68.82 ± 0.80 ***	64	60.51 ± 0.50***	116
	125	56.33 ± 1.45 ***		51.13 ± 0.56***
Rutin	1000	75.11 ± 1.41***		72.05 ± 0.86***
	500	66.72 ± 0.62***		62.47 ± 1.72***
	250	60.20 ± 2.35***	118	56.68 ± 0.70***	172
	125	48.09 ± 0.64***		45.00 ± 3.79***
Galanthamine	1000	97.24 ± 0.74		92.26 ± 0.92
	500	90.43 ± 0.50		86.51 ± 0.77
	250	79.00 ± 0.65	24	71.80 ± 0.48	54
	125	66.07 ± 1.46		62.43 ± 0.39

Galanthamine was used as a positive control. Data is represented as (mean ± S.E.M) n = 3. Values significantly different as compared to positive control, *: P < 0.05, **: P < 0.01, ***: P < 0.001, ns: P > 0.05

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