Fig. 5
From: Acteoside inhibits inflammatory response via JAK/STAT signaling pathway in osteoarthritic rats
ACT inhibits inflammatory cytokine production in synovial tissue of surgery-stimulated OA rats. SD rats were surgery-stimulated to induce OA and treated with ACT (100 mg/kg, i.p. injection). The generations of (a) IL-1β, (b) IL-6, (c) IL-12, (d) TNF-α and (e) IFN-γ in synovial fluid of knee joint were measured by ELISA assay. ** p < 0.01 and * p < 0.05 compared with sham group. # p < 0.05 compared with OA/NC group. The experiment was repeated three times and the representative results were shown