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Table 4 Effect of cisplatin (CP) and different treatments of AHE on lungs tissue antioxidant enzymes and GSH profile

From: Correction to: Acacia hydaspica R. Parker ameliorates cisplatin induced oxidative stress, DNA damage and morphological alterations in rat pulmonary tissue

Group

GSH

(μM/g tissue)

GR

(nM/min/mg protein)

GST

(nM/min/mg protein)

γ-GT

(nM/min/mg Protein)

GPx

(nM/min/mg Protein)

Control

16.12 ± 0.578b

143.7 ± 1.342b

98.85 ± 0.918b

295.4 ± 1.113b

107.4 ± 0.730b

CP

8.334 ± 0.356a

98.02 ± 0.619a

68.17 ± 0.962a

82.82 ± 0.958a

54.08 ± 0.909a

AHE alone

6.38 ± 0.207b

144.0 ± 1.492b

99.79 ± 1.865 b

295.6 ± 0.599b

108.8 ± 1.216b

CP + AHE

11.99 ± 0.305a,b, d

116.9 ± 0.813a,b,d

78.34 ± 1.076a,b**,d**

137.8 ± 1.017a,b,d

71.28.8 ± 0.501a,b,c

AHE + CP

15.63 ± 0.532b, c

135.0 ± 0.393 a,b,c

89.65 ± 1.49 a**,b,c

261.4 ± 0.802a,b,c

92.78 ± 1.216a,b,c

CP + Sily

15.29 ± 0.312b

133.8 ± 1.25 a,b

87.60 ± 1.644a,b

264.3 ± 1.067a,b

95.64 ± 1.573a,b

  1. Values expressed as mean ± SEM. a Significance at p < 0.0001 Vs. control group, b Significance at p < 0.0001 Vs. Cisplatin (CP) group. c Significance at p < 0.0001 of AHE + CP pre-treated group Vs. CP + AHE post-treated group. d Significance at p < 0.0001 of CP + AHE treatment groups Vs CP + Sily group. *, **: Significant difference at p < 0.001. Non-significant difference (p > 0.05) was recorded between control and AHE alone treated group in all parameters (One way ANOVA followed by Tukey’s multiple comparison tests)