From: Modulation of cancer signalling pathway(s) in two -stage mouse skin tumorigenesis by annonacin
Features/ Groups | Inflammation | Degeneration | Necrosis | Bowman capsule dilatation | Glomeruli cellularity | |||||
---|---|---|---|---|---|---|---|---|---|---|
Distribution (n = 10) | Mean score ± S.E.M | Distribution (n = 10) | Mean score ± S.E.M | Distribution (n = 10) | Mean score ± S.E.M | Distribution (n = 10) | Mean score ± S.E.M | Distribution (n = 10) | Mean score ± S.E.M | |
I (vehicle control) | 8 | 0.8 ± 0.1 | 0 | 0.0 ± 0.0 | 0 | 0.0 ± 0.0a | 0 | 0.0 ± 0.0 | 0 | 0.0 ± 0.0 |
II (carcinogen control) | 10 | 2.3 ± 0.2a | 2 | 0.2 ± 0.1a | 0 | 0.0 ± 0.0a | 6 | 0.6 ± 0.2a | 8 | 1.0 ± 0.2a |
III (treatment, annonacin) | 9 | 0.9 ± 0.1 | 0 | 0.0 ± 0.0 | 0 | 0.0 ± 0.0a | 0 | 0.0 ± 0.0 | 0 | 0.0 ± 0.0 |
IV (treatment control) | 6 | 0.5 ± 0.2 | 0 | 0.0 ± 0.0 | 0 | 0.0 ± 0.0a | 0 | 0.0 ± 0.0 | 0 | 0.0 ± 0.0 |
V (reference, curcumin) | 10 | 1.2 ± 0.1 | 0 | 0.0 ± 0.0 | 0 | 0.0 ± 0.0a | 0 | 0.0 ± 0.0 | 0 | 0.0 ± 0.0 |