Fig. 3
Effect of AE and NDGA on protein content (a) weight (b), and histology (c, d, e, f) in submandibular glands of streptozotocin-treated female rats. Rats were treated with streptozotocin (STZ) and euthanised on day 10 after treatment. a: The protein concentration was determined on gland homogenates. c, d, e and f: Representative light micrographs (200 X) of rat submandibular glands lobules. Glands were cut, fixed and stained with hematoxylin-eosin. Glands from a control animal (c), from a STZ-treated animal (d), from a STZ-treated animal + AE (e), from a STZ- treated animal + NDGA (f). AE: 500 μg/ml, NDGA: 1.5 μg/ml. Results represent Mean ± SEM of values from at least five glands. **P < 0.01 significant differences between submandibular glands from normal control and submandibular glands from STZ- treated animals (Student’s t test)