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Table 3 Cytotoxic effects of the mushroom extract in Vero cells

From: Anti-viral activity of culinary and medicinal mushroom extracts against dengue virus serotype 2: an in-vitro study

 

HAE

EE

ASE

ESE

HSE

P. giganteus

4211.8 ± 185.6**

319.5 ± 38.8**

> 10,000

171.8 ± 16.2**

163.8 ± 15**

L. rhinocerotis

3599.2 ± 417.8**

1967.2 ± 580.7*

3051 ± 244.6**

343.6 ± 5.3**

184.5 ± 19.2**

S. commune

4262.8 ± 1345.7*

> 500

> 10,000

>500

>500

H. erinaceus

5171.4 ± 1309.7*

817 ± 229.7*

> 10,000

150.7 ± 25.7**

60.6 ± 14.5*

G. lucidium

1748.1 ± 189.8**

175.3 ± 1.7**

779.1 ± 125**

>500

354.2 ± 3.6**

  1. The cytotoxicities of the mushroom extracts were measured at the end-point (48 h) by MTT assay. The CC50, 50% cytotoxic concentrations capable of reducing the absorbance by 50% in comparison to the negative control cells without extract, were estimated from dose response curves of three independent experiment using probit analysis (n = 3). Statistical differences compared to untreated cell control group are noted with asterisk (*P < 0.05) or (**p < 0.01)