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Fig. 6 | BMC Complementary and Alternative Medicine

Fig. 6

From: Berberine inhibits NLRP3 Inflammasome pathway in human triple-negative breast cancer MDA-MB-231 cell

Fig. 6

Effects of BBR on the expression profile of NLRP3 inflammasome signaling proteins in MDA-MB-231 cells. After treatment with various concentrations of BBR for 48 h, the protein bands (a) and (b), as well as expression profile of NLRP3 inflammasome signaling proteins, (c) P2X7, (d) pro-caspase1, (e) ASC, (f) NLRP3, (g) caspase-1 p20, (h) IL-1β and (i) IL-18, was analyzed using western blot as described in Material and methods. Significant difference between control and treatment with BBR are shown, * p < 0.05, ** p < 0.01. Representative image of the expression profile of each protein is shown from three independent experiments

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