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Table 2 Histopathological changes in all studied groups

From: Anti-inflammatory and nephroprotective activity of Juglans mollis against renal ischemia–reperfusion damage in a Wistar rat model

Experimental group

Intracellular vacualization

Medullary congestion

Proteinaceous casts

Exfoliated cells in the lumen

Tubular necrosis

Lymphocytes in peritubular capillares

Bowman’s space enlargement

Sham

1.17 ± 0.41

0.17 ± 0.41

0.67 ± 0.82

0.17 ± 0.41

0.00 ± 0.00

0.67 ± 0.52

0.33 ± 0.52

I/R

2.20 ± 0.45a

3.83 ± 0.41a

3.60 ± 0.55a

4.00 ± 0.00a

4.00 ± 0.00a

1.00 ± 0.00

2.80 ± 0.45a

JM

1.00 ± 0.00

1.00 ± 0.71

0.20 ± 0.45

0.40 ± 0.55

0.00 ± 0.00

1.00 ± 0.00

0.40 ± 0.55

JM + I/R

2.00 ± 0.00

0.50 ± .83b

2.00 ± 0.71b

2.80 ± 0.45b

2.00 ± 0.00b

1.00 ± 0.00

0.60 ± 0.89b

  1. Values represent the mean ± S.D. (n = 6) of histopathological grade. Grade: no change (0), mild (1), moderate (2), severe (3), very severe (4). a. p < 0.05, comparison with the sham group; b. p < 0.05, comparison with IR group