Bitter gourd (Momordica charantia) possess developmental toxicity as revealed by screening the seeds and fruit extracts in zebrafish embryos

Table 4 Teratogenic dose response of zebrafish embryos exposed to crude and fraction of fruit extract of Momordica charanti at 72hpf

Con. (μg/ml)	Developmental arrest^a		Cardiac toxicity^a		Blood circulation^a		Hatching^a
Con. (μg/ml)	Mean	± S.D	Mean	± S.D	Mean	± S.D	Mean	± S.D
Fruit crude
Control	0	0	0	0	0	0	0	0
1	0	0	0	0	0	0	0	0
5	0	0	0	0	0	0	0	0
15	0	0	0	0	0	0	0	0
20	0	0	0	0	0	0	0	0
25	0	0	0	0	0	0	0	0
30	0	0	0	0	0	0	0	0
50	0	0	100	0	100	0	0	0
Fruit C18 frac. #2
Control	0	0	0	0	0	0	0	0
1	0	0	0	0	0	0	0	0
5	0	0	5	0.25	0	0	0	0
10	0	0	100	0	100	0	0	0
15	0	0	100	0	100	0	0	0

^a Percentage of embryos showing the developmental defect. The values are the mean of three biological replication ± Standard deviation (S.D)

ISSN: 2662-7671