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Table 2 Teratogenic dose response of zebrafish embryos exposed to crude seed extract of M. charantia at 72hpf

From: Bitter gourd (Momordica charantia) possess developmental toxicity as revealed by screening the seeds and fruit extracts in zebrafish embryos

Concentration (μg/ml)

Developmental arresta

Cardiac toxicitya

Blood circulationa

Hatchinga

Mean

± S.D

Mean

±S.D

Mean

±S.D

Mean

± S.D

Control

0

0

0

0

0

0

0

0

1

0

0

0

0

0

0

0

0

5

0

0

85

0.33

85

0.33

0

0

10

0

0

100

0.00

100

0.00

5

0.67

15

0

0

100

0

100

0

100

0

20

100

0

100

0

100

0

100

0

25

100

0

100

0

100

0

100

0

30

100

0

100

0

100

0

100

0

  1. a Percentage of embryos with developmental defect. The values are the mean of three biological replication ± Standard deviation (S.D)