Table 1 Identification and quantification of proteins in Fraction 2

A0A1Q1N6G0

Major royal jelly protein 2 OS = Apis mellifera carnica GN = MRJP2 PE = 4 SV = 1

D3Y5T0

Major royal jelly protein OS = Apis mellifera GN = MRJP3 PE = 2 SV = 1

O77061

Major royal jelly protein 2 OS = Apis mellifera GN = MRJP2 PE = 1 SV = 1

A0A087ZRA1

Uncharacterized protein OS = Apis mellifera PE = 3 SV = 1

Q6IMJ9

Major royal jelly protein 7 OS = Apis mellifera GN = MRJP7 PE = 2 SV = 1

O18330

Major royal jelly protein 1 OS = Apis mellifera GN = MRJP1 PE = 1 SV = 1

A0A087ZW88

Uncharacterized protein OS = Apis mellifera PE = 4 SV = 1

A0A087ZQI5

ATP synthase subunit alpha OS = Apis mellifera GN = Atp5a1 PE = 3 SV = 1

A0A087ZRE3

Elongation factor 1-alpha OS = Apis mellifera GN = EF1a-F2 PE = 3 SV = 1

A0A088A436

Tubulin alpha chain OS = Apis mellifera GN = LOC550827 PE = 3 SV = 1

A0A088AN20

Uncharacterized protein OS = Apis mellifera GN = RpL40 PE = 4 SV = 1

Q4ZJX1

Major royal jelly protein 9 OS = Apis mellifera GN = MRJP9 PE = 2 SV = 1

A0A087ZQ27

Uncharacterized protein OS = Apis mellifera PE = 3 SV = 1

A0A088AMB8

ATP synthase subunit beta OS = Apis mellifera GN = Atp5b PE = 3 SV = 1

A0A088AEZ4

Tubulin alpha chain OS = Apis mellifera GN = LOC552766 PE = 3 SV = 1

A0A088A5A6

Uncharacterized protein OS = Apis mellifera GN = LOC409481 PE = 3 SV = 1

W8S9B2

Actin (Fragment) OS=Nosema ceranae PE = 3 SV = 1

H9KL77

Histone H4 OS = Apis mellifera GN = LOC724757 PE = 3 SV = 1

A0A087ZNX0

Uncharacterized protein OS = Apis mellifera GN = Rab11 PE = 4 SV = 1

A0A087ZSC1

Tubulin beta chain OS = Apis mellifera GN = LOC410559 PE = 3 SV = 1

A0A088AJJ6

Uncharacterized protein OS = Apis mellifera GN = LOC411989 PE = 3 SV = 1

A0A088AGJ8

Uncharacterized protein OS = Apis mellifera GN = LOC410620 PE = 3 SV = 1

A0A088A5X7

Uncharacterized protein OS = Apis mellifera GN = LOC409167 PE = 4 SV = 1

A0A088A3F4

Uncharacterized protein OS = Apis mellifera GN = LOC727045 PE = 4 SV = 1

A0A088A2A5

Uncharacterized protein OS = Apis mellifera GN = LOC552272 PE = 3 SV = 1

A0A087ZUL8

Uncharacterized protein OS = Apis mellifera GN = RpS15 PE = 3 SV = 1

A0A087ZR05

Uncharacterized protein OS = Apis mellifera GN = Rpn11 PE = 4 SV = 1

A0A087ZV73

Uncharacterized protein OS = Apis mellifera GN = LOC724873 PE = 4 SV = 1

A0A087ZMS7

Uncharacterized protein OS = Apis mellifera GN = Rab39 PE = 4 SV = 1

A0A088A6D6

Uncharacterized protein OS = Apis mellifera GN=Ndufs3 PE = 3 SV = 1

A0A088A7D1

Uncharacterized protein OS = Apis mellifera GN = LOC410306 PE = 3 SV = 1

A0A088A8F0

Putative H3K9 methyltransferase OS = Apis mellifera GN = 685996 PE = 4 SV = 1

A0A087ZYZ1

Tubulin beta chain OS = Apis mellifera GN = LOC408782 PE = 3 SV = 1

A0A0B4J2N0

Uncharacterized protein OS = Apis mellifera GN = LOC550794 PE = 3 SV = 1

A0A0B4J2L4

Uncharacterized protein OS = Apis mellifera GN = LOC410026 PE = 3 SV = 1

A0A088AIY2

Uncharacterized protein OS = Apis mellifera GN = mago PE = 4 SV = 1

A0A088AFT2

40S ribosomal protein S6 OS = Apis mellifera GN = LOC725647 PE = 3 SV = 1

A0A088ATI7

Uncharacterized protein OS = Apis mellifera GN = LOC409126 PE = 4 SV = 1

A0A087ZMT8

Uncharacterized protein OS = Apis mellifera PE = 4 SV = 1

A0A087ZZN8

Proteasome subunit alpha type OS = Apis mellifera GN=Prosalpha5 PE = 3 SV = 1

A0A087ZV06

40S ribosomal protein S8 OS = Apis mellifera GN = Rps8 PE = 3 SV = 1

A0A088A6T4

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS = Apis mellifera GN=SdhA PE = 3 SV = 1

A0A088ADQ6

Uncharacterized protein OS = Apis mellifera PE = 3 SV = 1

A0A088A2I2

UDP-glucose 6-dehydrogenase OS = Apis mellifera GN = LOC413356 PE = 3 SV = 1

A0A088A9V8

Uncharacterized protein OS = Apis mellifera PE = 3 SV = 1

A0A087EPB0

Cell division protein FtsZ OS = Lactobacillus kunkeei GN = ftsZ PE = 3 SV = 1

A0A088ANZ0

Uncharacterized protein OS = Apis mellifera GN = LOC551093 PE = 3 SV = 1

A0A088ARA9

60S ribosomal protein L13 OS = Apis mellifera GN = RpL13 PE = 3 SV = 1

A0A087EQF2

6-phosphogluconate dehydrogenase, decarboxylating OS = Lactobacillus kunkeei GN = JI66_01835 PE = 3 SV = 1

A0A088A2L4

Uncharacterized protein OS = Apis mellifera PE = 3 SV = 1

V5 T859

Glyceraldehyde-3-phosphate dehydrogenase OS=Bifidobacterium sp. Bin2N PE = 3 SV = 1

A0A088AEV2

Uncharacterized protein OS = Apis mellifera GN = RpL26 PE = 4 SV = 1

A0A087ZW54

Elongation factor Tu OS = Apis mellifera GN = LOC408328 PE = 3 SV = 1

A0A088AFM4

Uncharacterized protein OS = Apis mellifera GN = TER94 PE = 3 SV = 1

D3JZ08

MRJP5 OS = Apis mellifera PE = 2 SV = 1

A0A0B4J2P2

Uncharacterized protein OS = Apis mellifera GN = LOC551386 PE = 3 SV = 1

A0A088ATP8

Tubulin alpha chain OS = Apis mellifera PE = 3 SV = 1

A0A087ZUP0

Uncharacterized protein OS = Apis mellifera GN = 14–3-3epsilon PE = 3 SV = 1

A0A088AJ01

Mitogen-activated protein kinase OS = Apis mellifera GN = rl PE = 4 SV = 1

A0A087ZMS5

Uncharacterized protein OS = Apis mellifera PE = 4 SV = 1

A0A087EQE2

S-adenosylmethionine synthase OS = Lactobacillus kunkeei GN = metK PE = 3 SV = 1

A0A088A9W4

Uncharacterized protein OS = Apis mellifera GN=Flo1 PE = 3 SV = 1

A0A088ANC5

APD-3-like protein; Apidermin 1-like protein; Apidermin 3-like protein OS = Apis mellifera GN = apd-3 PE = 4 SV = 1