Table 4 Serum chemistry analysis after administration of Myelophil for 13 weeks
MYP (mg/kg, Number) | Male | Female | ||||||
|---|---|---|---|---|---|---|---|---|
0 (5) | 312.5 (3) | 625 (3) | 1250 (5) | 0 (5) | 312.5 (3) | 625 (3) | 1250 (5) | |
AST (IU/L) | 38.4 ± 9.6 | 48.0 ± 7.2 | 42.3 ± 12.1 | 47.8 ± 6.8 | 40.6 ± 5.1 | 44.0 ± 2.0 | 47.3 ± 16.4 | 44.0 ± 6.0 |
ALT (IU/L) | 40.0 ± 10.2 | 37.7 ± 9.1 | 31.3 ± 6.0 | 47.8 ± 19.8 | 36.8 ± 5.7 | 37.0 ± 5.6 | 40.0 ± 14.8 | 40.4 ± 10.4 |
ALP (IU/L) | 334.8 ± 97.7 | 494.0 ± 103.5 | 330.3 ± 116.6 | 345.2 ± 60.2 | 336.8 ± 120.0 | 219.3 ± 50.5 | 295.0 ± 10.4 | 289.4 ± 79.7 |
BUN (mg/dL) | 16.6 ± 2.4 | 17.4 ± 2.6 | 15.0 ± 2.3 | 14.3 ± 1.6 | 17.4 ± 4.8 | 17.0 ± 1.7 | 14.4 ± 2.7 | 14.4 ± 2.4 |
Creatinine (mg/dL) | 0.72 ± 0.03 | 0.66 ± 0.11 | 0.77 ± 0.06 | 0.82 ± 0.10 | 0.72 ± 0.13 | 0.63 ± 0.03 | 0.75 ± 0.05 | 0.72 ± 0.08 |
Glucose (mg/dL) | 89.8 ± 7.3 | 79.3 ± 3.8 | 84.3 ± 7.8 | 84.4 ± 9.5 | 86.6 ± 4.0 | 84.7 ± 3.1 | 92.0 ± 3.0 | 86.4 ± 9.6 |
Total cholesterol (mg/dL) | 184.0 ± 35.2 | 169.7 ± 27.2 | 151.7 ± 19.7 | 170.6 ± 37.3 | 160.0 ± 28.9 | 165.7 ± 34.6 | 150.3 ± 3.2 | 162.6 ± 32.2 |
Total protein (g/dL) | 5.5 ± 0.4 | 5.6 ± 0.2 | 5.6 ± 0.4 | 5.9 ± 0.3 | 5.8 ± 0.3 | 5.7 ± 0.4 | 5.8 ± 0.2 | 5.8 ± 0.4 |
CPK (U/L) | 242.6 ± 45.3 | 372.0 ± 152.2 | 307.0 ± 77.2 | 369.2 ± 122.9 | 256.0 ± 56.2 | 319.0 ± 79.7 | 362.3 ± 249.4 | 256.0 ± 75.6 |
Albumin (g/dL) | 2.6 ± 0.2 | 2.7 ± 0.1 | 2.6 ± 0.1 | 2.8 ± 0.1 | 2.7 ± 0.3 | 2.7 ± 0.3 | 2.9 ± 0.2 | 2.9 ± 0.2 |
Total bilirubin (mg/dL) | 0.04 ± 0.01 | 0.06 ± 0.02 | 0.04 ± 0.02 | 0.06 ± 0.03 | 0.07 ± 0.02 | 0.05 ± 0.02 | 0.06 ± 0.03 | 0.07 ± 0.02 |
A/G ratio | 0.89 ± 0.19 | 0.94 ± 0.02 | 0.87 ± 0.14 | 0.88 ± 0.07 | 0.88 ± 0.07 | 0.93 ± 0.09 | 0.98 ± 0.05 | 0.99 ± 0.04 |
Triglyceride (mg/dL) | 24.4 ± 3.6 | 44.0 ± 17.8 | 23.0 ± 4.0 | 30.4 ± 9.8 | 28.0 ± 2.9 | 28.0 ± 4.4 | 31.3 ± 6.1 | 30.2 ± 9.3 |
Calcium (mg/dL) | 10.3 ± 0.4 | 10.4 ± 0.4 | 10.2 ± 0.5 | 10.6 ± 0.5 | 10.3 ± 0.4 | 10.2 ± 0.5 | 10.3 ± 0.4 | 10.2 ± 0.6 |
Inorganic phosphorus (mg/dL) | 6.0 ± 0.7 | 6.0 ± 0.1 | 5.7 ± 0.7 | 5.8 ± 0.6 | 5.2 ± 0.4 | 4.9 ± 0.3 | 5.1 ± 1.3 | 4.8 ± 0.3 |
Chloride (mmol/L) | 112.4 ± 1.5 | 112.3 ± 0.6 | 110.7 ± 1.5 | 111.0 ± 2.0 | 109.8 ± 10.3 | 107.0 ± 1.7* | 109.7 ± 1.2 | 108.6 ± 0.9* |
Sodium (mmol/L) | 149.2 ± 1.3 | 148.0 ± 0.0 | 148.0 ± 1.0 | 148.0 ± 2.4 | 146.4 ± 1.5 | 144.0 ± 1.0* | 148.0 ± 1.7 | 145.8 ± 0.8* |
Potassium (mmol/L) | 5.3 ± 0.3 | 5.4 ± 0.2 | 5.4 ± 0.2 | 5.7 ± 0.2 | 5.0 ± 0.4 | 5.3 ± 0.2 | 5.3 ± 0.2 | 5.1 ± 0.2 |