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Table 1 Summary of the acute toxicity test in beagle dogs

From: Acute and repeated toxicological study of Myelophil, an ethanol extract of a mixture of Astragali Radix and Salviae Miltiorrhizae Radix, in beagle dogs

MYP (mg/kg)

0

1250

2500

5000

Number (M/F)

2 (1/1)

2(1/1)

2(1/1)

2 (1/1)

Mortality

Vomiting on the day of

administration

++ (M, F)

Vomiting on the day after of

administration

+ (F)

+ (F)

Compound-colored stool

+ (M)

Body weight change

Necropsy findings

NAD

NAD

NAD

NAD

  1. Beagle dogs in each group were fed Myelophil (MYP). Clinical signs were observed for 6 h after drug administration; thereafter, daily mortality and symptoms were observed for 2 weeks. At the end of the experiment, necropsy was performed
  2. M Male, F Female, NAD No abnormality detected; −: Absent; +: Slight; ++: Moderate