Evaluating the protective potency of Acacia hydaspica R. Parker on histological and biochemical changes induced by Cisplatin in the cardiac tissue of rats

Table 3 Effect of cisplatin (CP) and different treatments of extract AHE on cardiac tissue antioxidant enzymes

Group	POD (U/min)	SOD (U/mg protein)	CAT (U/min)	QR (nM/min/mg protein)
Control	10.66 ± 0.381	1.146 ± 0.037	15.76 ± 0.117	137.5 ± 0.735
CP	5.930 ± 0.537^***	0.742 ± 0.023^***	9.49 ± 0.1576^***	85.96 ± 0.358^***
AHE alone	10.92 ± 0.531⁺⁺⁺	1.145 ± 0.048⁺⁺⁺	15.66 ± 0.196⁺⁺⁺	137.7 ± 0.392⁺⁺⁺
CP + AHE	7.99 ± 0.572^**,+	0.992 ± 0.041+	11.89 ± 0.379^***,+++,###	117.5 ± 0.926^***,+++,###
AHE + CP	9.14 ± 0.081⁺⁺	1.074 ± 0.049⁺⁺⁺	14.84 ± 0.185⁺⁺⁺	133.3 ± 0.481^*,+++
CP + Sily	9.40 ± 0.231⁺⁺	1.094 ± 0.049⁺⁺⁺	14.73 ± 0.224⁺⁺⁺	131.7 ± 1.200^**,+++

Data are represented mean ± S.E.M (n = 6). Asterisks ^{*, **, ***} indicates p < 0.05, 0.001, 0.0001 vs. control; ^{+, ++, +++} indicates p < 0.05, 0.001, 0.0001 vs. CP alone; ^{#, ##, ###} indicates p < 0.05, 0.001, 0.0001 vs. AHE + CP. Non-significant difference (p > 0.05) was recorded between control and AHE alone treated group in all parameters (One way ANOVA followed by Tukey’s multiple comparison tests)

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