Table 2 Expression fold changes of S. aureus ST1792 biofilm related genes in berberine

 PIA

icaA

poly-beta-1,6-N-acetyl-D-glucosamine synthase

2.22

icaB

biofilm PGA synthesis lipoprotein PgaB

1.85

icaR

TetR/AcrR family transcriptional regulator

−2.32

spxA

regulatory protein spx

−1.42

srrB

sensor histidine kinase ResE

1.08

fnbA

fibronectin-binding protein A

1.53

fnbB

fibronectin-binding protein B

1.51

spa

immunoglobulin G-binding protein A

2.60

sasG

surface protein G

2.22

nuc

thermonuclease

2.02

cidA

holin-like protein

2.06

lrgA

murein hydrolase regulator LrgA

−2.59

lrgB

hydrolase activity

−2.71

agrABCD

accessory gene regulators

–

sigB

RNA polymerase sigma-B factor

–