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Table 2 Influence of the manufacturing process (Data table to Fig. 2)

From: Modulation of neurological pathways by Salvia officinalis and its dependence on manufacturing process and plant parts used

alpha 2A Muscarinic M3 μ-opioid
Test item IC50, μg dry mass/ml Test item IC50, μg dry mass/ml Test item IC50, μg dry mass/ml
Leaves (fresh) 11 Leaves (fresh) 22 Leaves (fresh) 16
Leaves + Stipes (fresh) 16 Leaves + Stipes (fresh) 28 Leaves + Stipes (fresh) 17
Leaves + Stipes (dry) 29 Leaves (dry) 41 Leaves + Stipes (dry) 20
Leaves (dry) 30 Leaves + Stipes (dry) 44 Leaves (dry) 24
Stipes (dry) 45 Stipes (fresh) 61 Stipes (dry) 33
Stipes (fresh) 46 Stipes (dry) 83 Stipes (fresh) 54
  1. Competition binding of different ethanolic Salvia officinalis extracts (highlighted in bold and italic: bold of fresh leaves, italic of dry stipes) at the adrenergic alpha 2A receptor, the muscarinic M3 receptor, and the human μ-opioid receptor. Data are the IC50 values of summary curves over 2 independent experiments performed in duplicate