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Fig. 6 | BMC Complementary and Alternative Medicine

Fig. 6

From: Methanol extract of semen Ziziphi Spinosae attenuates ethanol withdrawal anxiety by improving neuropeptide signaling in the central amygdala

Fig. 6

Effects of MESZS on the protein expressions of amygdaloid (a) CRF, (b) CRFR1 and (c) NOP during EtOHW. Immediately after the behavioral test, the protein expressions of CRF and CRFR1 and NOP in the CeA were detected using Western blot analysis. All data are expressed as a mean ± SEM (n = 4). S: saline, DW: distilled water, EtOH: ethanol, MESZS: methanol extract of Semen Ziziphi Spinosae, MESZS180: 180 mg/kg/d MESZS. # p < 0.05 and ### p < 0.001 vs. S/DW group; $ p < 0.05, $$ p < 0.01 $$$ p < 0.001 vs. EtOH/DW group; @@@ p < 0.001 vs. EtOH/MESZS180 group (one-way ANOVA followed by Newman-Keuls post hoc test)

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