Fig. 2

Effects of MESZS on the behavioral changes of rats in the open field test. All data are expressed as a mean ± SEM (n = 8). (a) The total distance traveled in the open field by rats. (b) Distance traveled in the center zone. (c) Time spent in the center zone. S: saline, DW: distilled water, MESZS: methanol extract of Semen Ziziphi Spinosae, MESZS60: 60 mg/kg/d MESZS, MESZS180: 180 mg/kg/d MESZS. ^# p < 0.05 and ^###p < 0.001 vs. S/DW group; ^$ p < 0.05 and ^$$ p < 0.01 vs. EtOH/DW group; ^@ p < 0.05 vs. EtOH/MESZS180 group (one-way ANOVA followed by Newman-Keuls post hoc test)