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Table 2 Effects of bromocriptine and/or BHE on reproductive hormones in male rats

From: Cannabinoid-deficient Benin republic hemp (Cannabis sativa L.) improves semen parameters by reducing prolactin and enhancing anti-oxidant status

 

Control

Bromocriptine

2 mg/kg Hemp extract

2 mg/kg Hemp extract + bromocriptine

10 mg/kg Hemp extract

10 mg/kg Hemp extract + bromocriptine

GnRH (pg/ml)

1382.7 ±

45.37

1389.4 ±

23.84

1243.2 ± 168.47

1399.1 ± 29.24

1371.7 ± 87.69

1405.5 ± 11.79

Prolactin (ng/ml)

8.17 ± 1.21

5.26 ± 0.20@

6.56 ± 0.37@

6.33 ± 0.56@

6.18 ± 0.35@

5.75 ± 0.47@

FSH (mIU/ml)

2.00 ± 0.46

2.25 ± 0.50

2.66 ± 0.53

2.36 ± 0.62

1.75 ± 0.23

6.43 ± 1.76@#$

LH (mIU/ml)

0.92 ± 0.05

0.93 ± 0.03

0.92 ± 0.06

0.76 ± 0.04

0.75 ± 0.06

0.80 ± 0.08

Testosterone (ng/ml)

0.47 ± 0.03

0.46 ± 0.03

0.49 ± 0.01

0.61 ± 0.03@#$

0.55 ± 0.04

0.65 ± 0.05@#$

Oestradiol (pg/ml)

1.96 ± 0.03

1.99 ± 0.08

1.92 ± 0.02

2.20 ± 0.24

1.92 ± 0.05

2.08 ± 0.11

  1. BHE denotes Benin republic hemp ethanol extract; GnRH denotes Gonadotropin releasing hormone; FSH denotes follicle stimulating hormone; LH denotes luteinising hormone
  2. @p < 0.05 vs. control; #p < 0.05 vs. bromocriptine; $p < 0.05 vs. corresponding BHE of same dose