Fig. 6

Representative images of aortic remodeling in different groups following HE staining (magnification, × 40). 1,control group; 2,model group; 3,L-NAME+AqE group; 4,L-NAME+XJEK group; 5,L-NAME+fosinopril group. The model group demonstrated notable vascular remodeling compared with the control group. However, these pathological changes could be markedly reversed following treatment with AqE for the last 4 weeks of treatment, and similar effects could be achieved when XJEK and the positive control fosinopril were administered