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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: The protective effects of polysaccharide extract from Xin-Ji-Er-Kang formula on Ang II-induced HUVECs injury, L-NAME-induced hypertension and cardiovascular remodeling in mice

Fig. 5

Effects of polysaccharide extract from XJEK on CVF and PVCA in L-NAME-induced hypertensive mice. Representative image of myocardial fibrosis following VG staining (magnification, × 400). (b) Statistic alanalysis of myocardial fibrosis. (c) Representative image of perivascular fibrosis following VG staining (magnification, × 400). (d) Statistical analysis of perivascular fibrosis. 1,control group; 2,model group; 3,L-NAME+AqE group; 4,L-NAME+XJEK group; 5,L-NAME+fosinopril group. Levels of myocardial and perivascular fibrosis increased significantly in the model group compared with control group. However, these pathological changes could be reversed following AqE for the last 4 weeks of treatment and similar effects could be achieved with treatment with the positive control fosinopril. Data are presented as the mean ± SD (n = 10). **P < 0.01 vs. control group; #P < 0.05, ##P < 0.01 vs. model group

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