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Table 2 Effect of postbiotic UL4 on cell cycle phases distribution of MCF-7 cells

From: Postbiotic metabolites produced by Lactobacillus plantarum strains exert selective cytotoxicity effects on cancer cells

 

Untreated control (%)

15% (v/v) (%)

30% (v/v) (%)

24 h

 Sub- G0/G1

0.5a ± 0.3

1.7ab ± 1.6

1.2a ± 1.0

 G0/G1

59.1ab ± 3.1

64.5bd ± 6.7

74.2b ± 9.5

 S

21.4a ± 4.2

16.4ac ± 3.6

12.8ac ± 5.7

 M

19.3a ± 1.6

17.6ac ± 3.3

12.3ac ± 3.5

48 h

 Sub- G0/G1

0.5a ± 0.2

14.3bc ± 5.6

15.5cd ± 1.7

 G0/G1

80.1bc ± 6.2

62.7be ± 2.1

56.3be ± 4.9

 S

9.4ac ± 3.7

13.7ac ± 2.7

13.3ac ± 3.0

 M

10.1ac ± 2.6

9.7ac ± 1.1

14.2ac ± 3.6

72 h

 Sub- G0/G1

0.5a ± 0.1

9.5abc ± 4.7

27.5d ± 1.2

 G0/G1

89.9c ± 1.4

70.2be ± 3.4

48.0ade ± 4.2

 S

3.3bc ± 0.4

9.9ac ± 1.1

12.7ac ± 1.2

 M

6.2bc ± 1.5

10.1ac ± 1.2

11.6ac ± 2.9

  1. Notes: The data represent the mean of percentage of cells. Values shown represent mean ± SEM. Values within the same row and column sharing a common superscript letter are not significantly different (P > 0.05)