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Table 1 IC50 values of PM produced by six strains of Lactobacillus plantarum on various cancer cells

From: Postbiotic metabolites produced by Lactobacillus plantarum strains exert selective cytotoxicity effects on cancer cells

  IC50 value of PM produced by L. plantarum strains, % (v/v)
Cancer Cells UL4 TL1 RS5 RG14 RG11 RI11
 MCF-7 (ATCC®HTB-22) 10 13 21 20 16 16
 HeLa (ATCC® CCL2) 20 18 24 20 N.D. 18
 Hep-G2 (ATCC®HB-8065) 22 22 27 22 N.D. N.D.
 HT-29 (ATCC®HTB-38) N.D. N.D. 28 22 N.D. N.D.
 K562 (ATCC®CCL-240) 10 5 5 5 5 5
 HL60 (ATCC®CCL-243) 5 5 9 10 1 1
  1. Notes: Human breast cancer cells MCF-7 (ATCC-HTB-22), colorectal cancer cells HT-29 (ATCC HTB-38), cervical cancer cells HeLa (ATCC CCL2) and liver cancer cells Hep-G2 (ATCC HB-8065) are anchorage-dependent cells while leukemia cells HL60 (ATCC CCL-240) and K562 (ATCC CCL-243) are suspension cells. The highest concentration of PM being tested on all cells was 30% (v/v). The IC50 values were detected after 72 h of incubation. The values reported are the means of nine replicates. N.D., no IC50 values were detected up to the concentration of 30% (v/v)