Table 1 Histological scoring parameter of epithelialization, angiogenesis, granulation tissue formation, and inflammatory cells
Parameter/Score | 0 | 1 | 2 | 3 |
|---|---|---|---|---|
Inflammatory cells | 1–5 inflammatory cells per histological field | 5–8 inflammatory cells per histological field | 8–11 inflammatory cells per histological field | 11–15 inflammatory cells per histological field |
Epithelialization | Absence of epithelial proliferation in ≥70% of tissue | Incomplete epidermal organization in ≥50% of tissue | Moderate epithelial proliferation in ≥60% of tissue | Complete epidermal remodeling in ≥80% of tissue |
Angiogenesis | Absence of angiogenesis including congestion and hemorrhage | 2–4 vessel per site, congestion and hemorrhage | 4–6 vessel per site, slight congestion | 7–8 vessel per site vertically disposed towards the epithelial surface |
Granulation Tissue | None, completely disorganized and distorted | Minimal/immature thin | Mild/moderately mature granule layer | Evident/ Thick, ≥80% organized |