Fig. 5
From: Preclinical evaluation of safety and potential of black hellebore extracts for cancer treatment
Residual migration (%) of cancer cells after treatment with HNE. Residual migration (%) of 14 cancer cell lines after treatment with HNE in two different concentrations (600 and 1000 μg/ml) compared to positive control SKI-606 in two concentrations (530 μg/ml, 5305 μg/ml) after 24–48 h depending on tumor cell lines. The cell line panel included gastric cancer (MKN-1), neuroblastoma (SK-N-SH), renal cell cancer, colorectal cancer (DLD-1), glioblastoma (LN 229 and U87-MG), cervical carcinoma (HeLa), lung cancer (HCC827), melanoma (A375 and A431), prostate carcinoma (DU-145), ovarian cancer (SK-OV3) and breast cancer (MDA-MB-231 and MCF-7). Value ranges over 100% do not mean a support of tumor cell migration but are rather due to artifact interactions in the assay