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Table 4 Effect of Placebo, Phyllanthus emblica 250 mg and Phyllanthus emblica 500 mg on lipid profile

From: Evaluation of the effects of a standardized aqueous extract of Phyllanthus emblica fruits on endothelial dysfunction, oxidative stress, systemic inflammation and lipid profile in subjects with metabolic syndrome: a randomised, double blind, placebo controlled clinical study

Parameter Placebo (A) (n = 18) Phyllanthus emblica 250 mg (B) (n = 20) Phyllanthus emblica 500 mg (C) (n = 21)
  Baseline 12 weeks Mean % change Baseline 12 weeks Mean % change Baseline 12 weeks 12 weeks Mean % change
TC (mg/dl) 179.16 ± 18.2 184.16 ± 20.8 2.78% 178.9 ± 21 165.7 ± 17.3 −7.17% 183.48 ± 23.8 162.5 ± 18.9 *† −11.11% †‡
HDL-C (mg/dl) 33.28 ± 2.74 33.29 ± 2.79 0.57% 32.75 ± 2.34 35.10 ± 4.24||¶ 7.33% 31.57 ± 2.44 38.48 ± 3.28 *† 22.16%†∞
LDL-C (mg/dl) 136.7 ± 16.02 141.6 ± 14.79 3.83% 133.2 ± 18.31 118.1 ± 17.9*† −11.39% 134.86 ± 12.24 105.52 ± 14.17*† −21.80%†∞
TG (mg/dl) 184.3 ± 19.82 184.7 ± 21.62 0.18% 184.4 ± 28.05 165.9 ± 23.43 −9.81% 198.19 ± 31.84 157.24 ± 18.12*† −19.22% †£
  1. Values expressed as mean ± SD
  2. SD Standard deviation, TC Total cholesterol, HDL-C High-density lipoprotein Cholesterol, LDL-C low-density lipoprotein cholesterol, TG Triglycerides
  3. *p < 0.001, ||p < 0.05 compared to baseline value. p < 0.001, §p < 0.01, p < 0.05 compared to placebo (A vs B, A vs C).p < 0.001 B vs C, £p < 0.01 B vs C, p < 0.05: B vs C