Skip to main content

Advertisement

Table 2 Effect of Placebo, Phyllanthus emblica 250 mg and  Phyllanthus emblica 500 mg on reflection index % (marker of endothelial function)

From: Evaluation of the effects of a standardized aqueous extract of Phyllanthus emblica fruits on endothelial dysfunction, oxidative stress, systemic inflammation and lipid profile in subjects with metabolic syndrome: a randomised, double blind, placebo controlled clinical study

Parameter Placebo (A) (n = 18)  Phyllanthus emblica 250 mg (B) (n = 20)  Phyllanthus emblica 500 mg (C) (n = 21)
RI (%) Baseline After treatment Baseline After treatment Baseline After treatment
4 weeks 8 weeks 12 weeks 4 weeks 8 weeks 12 weeks 4 weeks 8 weeks 12 weeks
Mean ± SD −2.27 ± 1.22 −1.88 ± 1.24 − 1.46 ± 1.61 − 0.97 ± 2.45 − 2.20 ± 0.97 − 2.39 ± 1.16 − 4.18 ± 0.87*† −8.82 ± 1.54*† −2.52 ± 1.13 −2.76 ± 0.99 − 4.86 ± 0.88*†‡ − 10.03 ± 1.58*†‡
p   NS NS NS   NS < 0.001 < 0.001   NS < 0.001 < 0.001
  1. Values expressed as mean ± SD
  2. SD standard deviation, RI Reflection index
  3. *p < 0.001: compared to baseline value. p < 0.001: compared to placebo (A vs B, A vs C), p < 0.05: B vs C