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Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Effect of Celastrus orbiculatus in inhibiting Helicobacter pylori induced inflammatory response by regulating epithelial mesenchymal transition and targeting miR-21/PDCD4 signaling pathway in gastric epithelial cells

Fig. 1

Effect of COE on H. pylori infection-induced cell morphological and inflammatory cytokine changes. (a) The effects of COE toxicity on cell viability of GES-1 cells after 24, 48, 72 h culture. The cell viability showed the results of three separate experiments as mean ± SD, *P < 0.05, **P < 0.01, vs 0 μg/mL. (b) The effects of COE on H. pylori-infected cell morphological changes. Representative pictures of cells were obtained under a microscope at × 200 magnification. (c) The effects of COE on H. pylori-induced pro-inflammatory cytokine changes. ELISA was applied to test the levels of IL-6, IL-8 and TNF-α. Data are presented as mean ± SD of three separate experiments, *P < 0.05, **P < 0.01 compared with the H. pylori-infected group

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