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Table 3 Mortality associated with the TCM users, by duration of TCM use and TCM use status

From: Traditional Chinese medicine use is associated with lower end-stage renal disease and mortality rates among patients with diabetic nephropathy: a population-based cohort study

 

Death

PY

Ia

Before matched

After matched

aHR$ (95% CI)

Sig.

aHR$ (95% CI)

Sig.

Duration of TCM use (days)

 TCM nonuser

14,588

170,815.5

85.4

1 (reference)

 

1 (reference)

 

  ≤ 60

6144

114,886.8

53.5

0.55 (0.54–0.57)

***

0.56 (0.54–0.57)

***

 61–120

1236

27,672.5

44.7

0.47 (0.44–0.49)

***

0.47 (0.44–0.50)

***

 121–180

566

13,663.0

41.4

0.40 (0.37–0.43)

***

0.43 (0.39–0.46)

***

 181–240

311

8969.5

34.7

0.36 (0.33–0.40)

***

0.36 (0.32–0.40)

***

 241–

916

32,473.4

28.2

0.29 (0.27–0.30)

***

0.29 (0.28–0.31)

***

TCM use status

 Never user

10,699

127,149.0

84.1

1 (reference)

 

1 (reference)

 

 Former user

3889

43,666.6

89.1

1.01 (0.98–1.05)

 

1.02 (0.98–1.06)

 

 Current user

5530

113,624.6

48.7

0.49 (0.47–0.50)

***

0.49 (0.48–0.51)

***

 New user

3643

84,040.59

43.3

0.47 (0.45–0.48)

***

0.47 (0.46–0.49)

***

  1. *Significance: *p-value <.05; **p-value <.01; ***p-value <.001
  2. aIncidence is presented as 1000 person-year (PY)
  3. $Age, gender, geolocation, insured level, comorbidities, medications, previous TCM experience, were adjusted in the Cox regression model to evaluate the hazard ratio for all-cause mortality