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Table 1 Effect of 1-(2-(2-(2-(1-aminoethyl)phenyl)diselanyl)phenyl)ethanamine (APDP) on hepatic TBARS (Thiobarbituric acid reactive substances), NPSH (Non-protein thiol) and δ-ALA-D (Delta-aminolevulinic acid dehydratase) of mice

From: Acute oral toxicity and antioxidant studies of an amine-based diselenide

Groups(mg/kg) TBARSa NPSH b δ-ALA-Dc
Control 28.3 ± 1.2 8.3 ± 0.4 25.3 ± 3.4
APDP-10 30.2 ± 11.1 8.5 ± 2.0 23.5 ± 2.3
APDP-100 29.3 ± 2.1 8.2 ± 2.1 26.3 ± 1.5
APDP-350 33.1 ± 2.1 9.1 ± 2.9 25.2 ± 1.6
  1. Data are reported as mean ± S.D. Data are reported as mean ± SD of seven animals per group. (*) Denoted p < 0.05 as compared to all groups (one-way ANOVA/Duncan). Data are expressed as anmol equivalents MDA (malondialdehyde) mg-1 protein, bμg ascorbic acid g-1 tissue, cU mg-1 protein and nmol of porphobilinogen mg-1 protein hour-1.