Fig. 1

Antinociceptive effect of PECN assessed using the acetic acid–induced abdominal constriction in mice. Animals were treated with vehicle (10 mL/kg, p.o.), ASA (100 mg/kg, p.o.), or PECN (100, 250, 500 mg/kg, p.o.) 60 min before acetic acid (0.6%, 10 mL/kg, i.p.) treatment. Each column represents the mean ± SEM of six mice. Statistical analyses were performed using one–way ANOVA followed by Dunnett’s post hoc test. *** p < 0.001 compared to control group. Values in parentheses denote percentage of inhibition