Skip to main content

Table 1 IC50 values (μg/mL) of ferric reducing power, DPPH, PDE-5, arginase, ACE and AChE inhibitory activities in rat penile and testicular tissue by O. gratissimum leaf extracts and standard drugs/inhibitors

From: Ocimum gratissimum Linn. Leaves reduce the key enzymes activities relevant to erectile dysfunction in isolated penile and testicular tissues of rats

Sample

PDE-5 (μg/mL)

Arginase (μg/mL)

ACE (μg/mL)

AChE (μg/mL)

FRAP (μg/mL)

DPPH (μg/mL)

Penis

43.19 ± 0.02c

46.12 ± 0.15c

44.23 ± 0.71a

55.51 ± 0.45a

–

–

Testes

44.67 ± 0.01b

49.12 ± 0.12b

53.99 ± 0.85a

60.03 ± 0.34a

–

–

Sildenafil (μg/mL)

26.65 ± 0.10a

–

–

–

–

–

L-NOHA (μg/mL)

–

42.48 ± 0.21a

–

–

–

–

Lisinopril (μg/mL)

–

–

38.34 ± 0.01a

–

–

–

Prostigmine (μg/mL)

–

–

–

48.01 ± 1.02a

–

–

Vitamin C (μg/mL)

–

–

–

–

46.16 ± 0.51a

53.81 ± 0.02a

O. gratissimum extract

–

–

–

–

56.55 ± 0.78a

69.41 ± 0.01a

  1. Values represent mean ± standard deviation (n = 3). Values with the same superscript along the column are not significant (p < 0.05) different. Sildenafil*: standard drug for phosphodiesterase-5 (PDE-5); L-NOHA*: standard inhibitor for arginase; prostigmine*: standard drugs for AChE; Lisinopril*: standard drug for ACE; Vitamin C*: standard drug for ferric reducing power (FRAP) and DPPH