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Table 2 The top 10 significantly up-regulated DEGs and down-regulated DEGs

From: Deciphering the mechanism of Indirubin and its derivatives in the inhibition of Imatinib resistance using a “drug target prediction-gene microarray analysis-protein network construction” strategy

Group

Genesymbol

Gene Description

Fold Change

Upregulated genes

CCL13

C-C motif chemokine 13

9.39035

MAPK11

Mitogen-activated protein kinase 11

7.52975

PDCD4

Programmed cell death protein 4

7.43475

BCL2

Bcl2-associated agonist of cell death

7.22081

CCL27

C-C motif chemokine 27

6.79919

TCEB3B

transcription elongation factor B subunit 3B

6.65061

ANAPC10

anaphase promoting complex subunit 10

6.21695

IL1R1

interleukin 1 receptor type 1

6.14025

TCF4

transcription factor 4

5.79877

TFAP2A

transcription factor AP-2 alpha

5.65156

Downregulated genes

MLH1

MutL homolog 1

−10.7446

BCL10

B-cell CLL/lymphoma 10

−8.27759

MAP3K4

mitogen-activated protein kinase kinase kinase 4

−8.1475

CDK9

cyclin dependent kinase 9

−6.66841

APOB

apolipoprotein B

−6.5818

PDGFC

platelet derived growth factor C

−6.62762

IL10RA

interleukin 10 receptor subunit alpha

−5.64569

IL12A

interleukin 12A

−5.49548

CDC14A

cell division cycle 14A

−5.20635

ALOX5

arachidonate 5-lipoxygenase

−5.20383