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Table 4 Cytotoxic effect of E. chilensis extracts (IC50 μg / mL) for different cell lines compared to an antineoplastic drug

From: In vitro antioxidant and antiproliferative effect of the extracts of Ephedra chilensis K Presl aerial parts

Extract/Sample

MCF-7

HT-29

PC-3

DU-145

CoN

Hex

0.31 ± 0.02a

3.67 ± 0.18a

0.43 ± 0.11a

4.25 ± 0.51a

2.82 ± 0.85a

CH2Cl2

0.28 ± 0.09a

2.07 ± 0.39a

0.38 ± 0.18a

1.93 ± 0.58b

1.19 ± 0.66a

EtOH

1.29 ± 0.13b

i

5.02 ± 2.45b

4.96 ± 0.12a

5.05 ± 0.60b

Doxo.

1.10 ± 5.0.12b

0.55 ± 0.05b

2.75 ± 0.50c

0.55 ± 0.06c

5.50 ± 0.53b

  1. Different letters in the same column indicate significant differences; p < 0.05, n = 3; i = inactive at maximal concentration 10 μg / mL; Doxo. = Doxorubicin