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Table 2 Antimicrobial activity in μg mL-1 of compounds from P. lentiscus

From: Compounds from Olea europaea and Pistacia lentiscus inhibit oral microbial growth

P. lentiscus

Sample (% dilution in DMSO)

24Z-isomasticadienolic acid (3.9%)

oleanolic acid (2.6%)

oleanonic aldehyde (2.4%)

DMSO (in %)

c / μg mL− 1

MICa

MBCb

MIC

MBC

MIC

MBC

MIC

MBC

Streptococcus mutans DSM 20523

78

156

19.5

39

1250

1250

6.00

25.00

Streptococcus sobrinus DSM 20381

39

1250

19.5

39

1250

1250

10.00

15.00

Streptococcus oralis ATCC 35037

39

78

19.5

78

1250

1250

10.00

10.00

Enterococcus faecalis ATCC 29212

156

1250

78

312

1250

1250

15.00

25.00

Candida albicans DSM 1386

1250

1250

1250

1250

1250

1250

8.00

8.00

Escherichia coli ATCC 25922

1250

1250

1250

1250

1250

1250

10.00

10.00

Staphylococcus aureus ATCC 25923

1250

1250

78

1250

1250

1250

10.00

25.00

Porphyromonas gingivalis W381

2.4

9.8

9.8

9.8

625

1250

12.50

12.50

Prevotella intermedia ATCC 25611

NA

NA

NA

NA

NA

NA

3.12 (5d)

3.12

Fusobacterium nucleatum ATCC 25586

625

625

625

625

1250

1250

6.25

6.25

Parvimonas micra ATCC 23195

2.4

9.8

625

1250

1250

1250

6.25 (5d)

12.50

  1. NA No activity observed: MIC or MBC were measured at 1250 μg mL−1, 5d = values yielded after 5 days of incubation, aMIC = extract concentration at which the optical density (OD) measurement revealed minimal bacterial growth, bMBC = extract concentration at which a three log reduction (99.9%) of the bacterial growth was induced