Table 1 Antimicrobial activity in μg mL-1 of compounds from O. europaea
From: Compounds from Olea europaea and Pistacia lentiscus inhibit oral microbial growth
O. europaea | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sample (% dilution in DMSO) | oleuropein (1.8%) | hydroxytyrosol (1.25%) | oleocanthal (2.1%) | oleacein (1.1%) | maslinic acid (6.6%) | DMSO in % | ||||||
c / μg mL−1 | MICa | MBCb | MIC | MBC | MIC | MBC | MIC | MBC | MIC | MBC | MIC | MBC |
Streptococcus mutans DSM 20523 | 625 | 625 | 312 | 312 | 1250 | 1250 | 1250 | 1250 | 19.5 | 156 | 6.00 | 25.00 |
Streptococcus sobrinus DSM 20381 | 625 | 1250 | 625 | 1250 | 312 | 1250 | 1250 | 1250 | 19.5 | 19.5 | 10.00 | 15.00 |
Streptococcus oralis ATCC 35037 | 1250 | 1250 | 1250 | 1250 | 1250 | 1250 | 1250 | 1250 | 19.5 | 19.5 | 10.00 | 10.00 |
Enterococcus faecalis ATCC 29212 | 1250 | 1250 | 1250 | 2500 | 1250 | 1250 | 1250 | 1250 | 39 | 312 | 15.00 | 25.00 |
Candida albicans DSM 1386 | 1250 | 1250 | 1250 | 2500 | 625 | 1250 | 1250 | 1250 | 1250 | 1250 | 8.00 | 8.00 |
Escherichia coli ATCC 25922 | 1250 | 1250 | 1250 | 2500 | 1250 | 1250 | 1250 | 1250 | 1250 | 1250 | 10.00 | 10.00 |
Staphylococcus aureus ATCC 25923 | 625 | 625 | 312 | 312 | 1250 | 1250 | 625 | 625 | 78 | 625 | 10.00 | 25.00 |
Porphyromonas gingivalis W381 | 625 | 625 | 156 | 312 | 156 | 312 | 312 | 625 | 4.9 | 9.8 | 12.5 | 12.5 |
Prevotella intermedia ATCC 25611 | NA | NA | 312(5d) | NA | NA | NA | 625 (5d) NA | Â | NA | NA | 3.12 (5d) | 3.12 |
Fusobacterium nucleatum ATCC 25586 | 625 | 312 | 312 | 312 | 312 | 312 | 156 | 156 | 312 | 25 | 6.25 | 6.25 |
Parvimonas micra ATCC 23195 | 1250 | 1250 | 1250 | 1250 | 312 | 312 | 1250 | 1250 | 9.8 | 9.8 | 6.25 (5d) | 12.5 |