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Table. 3 Effects of YHHY Decoction treatment on antioxidant parameters in rats breast tissues

From: Multi-targeting chemoprevention of Chinese herb formula Yanghe Huayan decoction on experimentally induced mammary tumorigenesis

Group

SOD

(U/mg protein)

GPx

(U/mg protein)

CAT

(U/mg protein)

MDA

(nmol/mg protein)

NOx

(μmol/mg protein)

(A) Raw data

A-Control (n = 10)

2.68 ± 0.19

0.23 ± 0.02

624.5 ± 36.9

3.07 ± 0.37

5.84 ± 0.45

B-DMBA (n = 14)

4.12 ± 0.46

0.37 ± 0.06

520.1 ± 29.4

4.18 ± 0.42

8.99 ± 0.64

C-YHHY+DMBA (n = 18)

2.64 ± 0.33

0.19 ± 0.04

531.7 ± 31.7

3.02 ± 0.31

5.79 ± 0.47

D-YHHY (n = 10)

2.78 ± 0.12

0.24 ± 0.02

629.5 ± 29.2

3.19 ± 0.21

5.11 ± 0.39

(B) Statistical comparison

 Group A vs B

< 0.01

< 0.01

< 0.01

< 0.01

< 0.01

 Group B vs C

< 0.01

< 0.01

0.44

< 0.01

< 0.01

 Group A vs C

0.41

0.32

< 0.001

0.47

0.38

 Group A vs D

> 0.05

> 0.05

> 0.05

> 0.05

> 0.05

  1. SOD superoxide dismutase, GPx glutathione peroxidase, CAT catalase, MDA malondialdehyde, NOx nitrate
  2. (A) Raw data given as mean ± S.E.M. (B) Statistical analysis (Tukey’s two-way comparisons) of the data shown in part A