Table. 2 Top function networks of the YHHY Decoction chemical components and their 293 interacting molecules in IPA
Categories | Disease or Function Annotation | p-Value | # Molecules |
|---|---|---|---|
Cell Death and Survival | apoptosis | 5.16E-25 | 59 |
Cellular Function and Maintenance | cellular homeostasis | 1.91E-22 | 46 |
Tissue Morphology | Quantity of cells | 1.1E-22 | 42 |
Cellular Development, Cellular Growth and Proliferation | Cell proliferation of tumor cell lines | 3.38E-21 | 41 |
Inflammatory Response, Organism Injuries and Abnormalities | inflammation of organ | 5.02E-27 | 38 |
Cardiovascular System Development and Function | development of vasculature, angiogenesis | 9.15E-22 | 37 |
Free Radical Scavenging | synthesis of reactive oxygen species | 4.2E-24 | 36 |
Cell Cycle | cell cycle progression | 5.47E-14 | 31 |
Cellular Movement | invasion of cells | 1.08E-18 | 31 |
Cancer, Cell Death and Survival, Tumor Morphology | Cell death of cancer cells | 1.28E-24 | 29 |