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Table 1 Cross-sectional geometric properties of the tibia midshaft

From: Exercise and resveratrol increase fracture resistance in the 3xTg-AD mouse model of Alzheimer’s disease

 

Wild type

3xTg-AD control

3xTg-AD resveratrol

3xTg-AD exercise

3xTg-AD resveratrol + exercise

Length (mm)

19.5 ± 0.15

19.2 ± 0.13

19.1 ± 0.15

19.3 ± 0.17

19.3 ± 0.15

Diameter (mm)

0.69 ± 0.03

0.69 ± 0.02

0.69 ± 0.03

0.70 ± 0.05

0.76 ± 0.04*

Tt.Ar (mm2)

0.86 ± 0.04

0.78 ± 0.26

0.84 ± 0.03

0.83 ± 0.10

0.93 ± 0.03*

M.Ar (mm2)

0.27 ± 0.02

0.17 ± 0.01

0.19 ± 0.01

0.18 ± 0.02

0.20 ± 0.01

Ct.Ar (mm2)

0.59 ± 0.03

0.60 ± 0.02

0.64 ± 0.03

0.64 ± 0.07

0.74 ± 0.03*

Imax (×10−2, mm4)

7.51 ± 0.78

6.69 ± 0.37

7.34 ± 0.73

8.06 ± 1.45

9.58 ± 0.83*

Imin (× 10− 2, mm4)

4.33 ± 0.45

3.78 ± 0.33

4.68 ± 0.51

4.73 ± 0.78

5.65 ± 0.45*

J (×10−2, mm4)

11.8 ± 1.20 0.06

10.5 ± 0.69

12.0 ± 1.22

12.8 ± 2.22

15.2 ± 1.24*

  1. Data displayed as mean ± SE; Tt.Ar, total area; M.Ar, medullary area; Ct.Ar, cortical area; Imax, maximum second moment of area; Imin, minimum second moment of area; J, polar moment of area. *, P < 0.05 in comparison with 3xTg-AD control