BMC Complementary Medicine and Therapies

Table 2 Bactericidal efficacy of fatty acids against logarithmic and stationary phases of Borrelia burgdorferii s.s. and Borrelia garinii

From: Anti-borreliae efficacy of selected organic oils and fatty acids

Tested fatty acids	Borrelia burgdorferi s.s.		Borrelia garinii
Tested fatty acids	Logarithmic phase MBC₉₀ (mg/ml)	Stationary phase MBC₉₀ (mg/ml)	Logarithmic phase MBC₉₀ (mg/ml)	Stationary phase MBC₉₀ (mg/ml)
Polyunsaturated
Linolenic acid	NS^a	NS^a	NS^a	NS^a
Eicosapentaenoic acid	NS^a	NS^a	NS^a	NS^a
Docosahexaenoic acid	NS^a	NS^a	NS^a	NS^a
Linoleic acid	1.0	1.0	1.0	1.0
13Z,16Z Docosadienoic acid	0.5	0.5	0.5	0. 5
Monounsaturated
Undecenoic acid	NS^a	NS^a	NS^a	NS^a
Palmitoleic acid	NS^a	NS^a	NS^a	NS^a
Oleic acid	1.0	1.0	1.0	1.0
Erucic acid	0.75	0.75	0.75	0.70
Petroselinic acid	0.75	0.75	0.75	0.75
Saturated
Butyric acid	1.0	1.0	1.0	1.0
Undecanoic acid	NS^a	NS^a	NS^a	NS^a
Caprylic acid	NS^a	NS^a	NS^a	NS^a
Myristic acid	NS^a	NS^a	NS^a	NS^a
Palmitic acid	NS^a	NS^a	NS^a	NS^a
Stearic acid	NS^a	NS^a	NS^a	NS^a
Arachidic Acid	1.0	1.0	1.0	1.0
Dox + Dap+Cef	0.03	0.03	0.03	0.03

Abbreviations: MBC₉₀–minimal bactericidal concentration causing at least 90% of killing assessed using spectrofluorimetry after 72 h of treatment, Dox doxycycline, Dap daptomycin, Cef cefoperazon, ^a–maximal tested concentration (i.e., 1%), NS–not susceptible/not satisfying MBC₉₀ requirement at the maximal tested concentration

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