Fig. 1

Effects of RL on mice glucose metabolism and urine volume after treatment for 4 weeks (n = 8). a OGTT (Mice were fasted overnight and fed with D-glucose at 2 g/kg body weight, plasma glucose was measured at 0, 15, 30, 60, and 120 min after glucose challenge), (b) Area under the curve (AUC_0-2h) of the blood glucose (Bg) time course from 0 to 120 min (Formula: AUC0-2 h = (Bg0 + Bg15) × 0.5 ÷ 4 + (Bg15 + Bg30) × 0.5 ÷ 4 + (Bg30 + Bg60) × 0.5 ÷ 2 + (Bg60 + Bg120) × 0.5), (c) Plasma insulin levels and (d) 5 h urine volume in five groups mice. Model vs. control group ^**P < 0.01