Table 4 Effect of oral administration of OE on serum biochemical profiles
Tests | Male | Female | ||||||
|---|---|---|---|---|---|---|---|---|
G1 | G2 | G3 | G4 | G1 | G2 | G3 | G4 | |
AST (U/L) | 118.1 ± 15.9 | 110.0 ± 15.5 | 102.6 ± 13.2 | 114.3 ± 10.4 | 80.5 ± 11.0 | 81.3 ± 3.4 | 84.3 ± 14.7 | 85.9 ± 11.4 |
ALT (U/L) | 27.0 ± 3.9 | 32.9 ± 7.5 | 27.4 ± 4.4 | 29.5 ± 4.2 | 21.6 ± 2.6 | 22.3 ± 3.2 | 18.0 ± 1.0 | 34.1 ± 2.4** |
ALP (U/L) | 190.4 ± 5.3 | 213.1 ± 39.1 | 192.3 ± 3.5 | 210.2 ± 42.6 | 135.0 ± 41.5 | 121.7 ± 13.3 | 126.8 ± 23.6 | 145.6 ± 27.3 |
CPK (U/L) | 763.0 ± 156.9 | 578.3 ± 113.2 | 525.0 ± 16.6 | 628.3 ± 227.0 | 216.0 ± 14.7 | 232.0 ± 63.0 | 262.3 ± 217.2 | 181.0 ± 68.1 |
TBIL (mg/dL) | 0.11 ± 0.02 | 0.11 ± 0.01 | 0.12 ± 0.02 | 0.11 ± 0.02 | 0.11 ± 0.01 | 0.11 ± 0.02 | 0.10 ± 0.02 | 0.14 ± 0.01* |
GLU (mg/dL) | 97.6 ± 5.4 | 110.7 ± 13.2 | 122.4 ± 27.7 | 108.1 ± 29.4 | 117.1 ± 6.4 | 122.0 ± 5.2 | 120.2 ± 3.5 | 110.2 ± 11.4 |
TCHO (mg/dL) | 84.0 ± 10.4 | 75.7 ± 3.2 | 82.7 ± 3.8 | 79.3 ± 13.7 | 72.7 ± 9.0 | 75.7 ± 7.6 | 72.7 ± 8.3 | 77.3 ± 10.1 |
TG (mg/dL) | 99.3 ± 7.6 | 74.7 ± 13.8 | 95.3 ± 25.7 | 88.3 ± 17.2 | 37.3 ± 5.0 | 28.0 ± 4.0 | 25.7 ± 5.0* | 42.7 ± 6.0 |
TP (g/dL) | 5.44 ± 0.19 | 5.40 ± 0.26 | 5.50 ± 0.14 | 5.44 ± 0.29 | 5.53 ± 0.10 | 5.42 ± 0.19 | 5.49 ± 0.25 | 5.33 ± 0.19 |
Albumin (g/dL) | 2.92 ± 0.10 | 2.89 ± 0.09 | 2.93 ± 0.09 | 2.89 ± 0.13 | 3.05 ± 0.05 | 3.02 ± 0.12 | 3.04 ± 0.11 | 2.97 ± 0.14 |
A/G ratio | 1.16 ± 0.02 | 1.16 ± 0.05 | 1.14 ± 0.06 | 1.14 ± 0.04 | 1.23 ± 0.05 | 1.26 ± 0.03 | 1.25 ± 0.06 | 1.26 ± 0.07 |
BUN (mg/dL) | 9.6 ± 0.9 | 13.2 ± 0.8** | 14.9 ± 1.5** | 13.0 ± 1.4** | 15.6 ± 2.3 | 14.2 ± 1.6 | 15.8 ± 3.1 | 13.7 ± 0.9 |
CRE (mg/dL) | 0.37 ± 0.01 | 0.40 ± 0.05 | 0.36 ± 0.03 | 0.36 ± 0.03 | 0.42 ± 0.08 | 0.39 ± 0.02 | 0.37 ± 0.01 | 0.37 ± 0.04 |
IP (mg/dL) | 8.95 ± 0.29 | 8.96 ± 0.31 | 8.79 ± 0.21 | 8.52 ± 0.22 | 7.88 ± 0.19 | 7.88 ± 0.41 | 7.52 ± 0.48 | 7.49 ± 0.51 |
Ca2+ (mmol/L) | 9.80 ± 0.13 | 9.76 ± 0.11 | 9.87 ± 0.20 | 9.65 ± 0.30 | 9.85 ± 0.15 | 9.86 ± 0.12 | 9.90 ± 0.12 | 9.91 ± 0.07 |
Na+ (mmol/L) | 141.8 ± 2.8 | 143.0 ± 0.8 | 141.9 ± 0.9 | 141.5 ± 0.6 | 140.2 ± 0.8 | 140.5 ± 1.3 | 141.5 ± 0.4 | 140.7 ± 0.5 |
K+ (mmol/L) | 5.05 ± 0.57 | 4.91 ± 0.37 | 4.99 ± 0.17 | 4.87 ± 0.56 | 4.84 ± 0.34 | 4.84 ± 0.13 | 4.62 ± 0.08 | 4.41 ± 0.14 |
Cl− (mmol/L) | 98.9 ± 2.8 | 101.0 ± 2.0 | 99.8 ± 0.9 | 99.9 ± 1.0 | 103.5 ± 1.1 | 103.7 ± 1.5 | 103.9 ± 1.3 | 102.6 ± 1.2 |