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Fig. 5 | BMC Complementary and Alternative Medicine

Fig. 5

From: 2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cells

Fig. 5

The analysis of cell apoptosis and cell cycle distribution of HCC CSCs induced by 2-ethoxystypandrone (1). a. 2-Ethoxystypandrone (1) induced cell apoptosis of HCC CSCs in dose-dependent manner. Apoptosis rates of HCC CSCs after being treated with 2-ethoxystypandrone (1) at the indicated concentration for 24 h. b. The cell cycle distribution of HCC CSCs after being treated with 2-ethoxystypandrone (1) at the concentration of 10 μM for 24 h. Values are means+SEM, *p < 0.05 and ***p < 0.001, compared to control group. Two-tailed unpaired T-Test was used for statistical analysis by SPSS 19.0 software

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