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Fig. 2 | BMC Complementary and Alternative Medicine

Fig. 2

From: Absence of herb-drug interactions of mistletoe with the tamoxifen metabolite (E/Z)-endoxifen and cytochrome P450 3A4/5 and 2D6 in vitro

Fig. 2

Apoptosis induction in MCF-7 cells by treatment with endoxifen or VAEM for 5 days. Flow cytometric analysis of apoptotic death in MCF-7 cells labeled with annexin-V FITC and 7-AAD in the presence (top) and absence (bottom) of 0.5 μM β-estradiol (E2). This figure is representative of three independent experiments. The percentages in the graphs represent the percentage of cell numbers in each quadrant. Q1 and Q2: late apoptotic/necrotic cells, Q3: early apoptotic cells, Q4: viable cells

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