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Table 2 Cytokines and receptors showing significant differential gene expression level in the liver of infected AG129 mice treated with FCPLJa compared to infected AG129 mice without treatment

From: Effect of freeze-dried Carica papaya leaf juice on inflammatory cytokines production during dengue virus infection in AG129 mice

Gene target

Description

Fold regulationb

P valuec

CCL12

Chemokine (c-c motif) ligand 12

−2.31

0.000161

CCL17

Chemokine (c-c motif) ligand 17

−2.76

0.013469

CCL6

Chemokine (c-c motif) ligand 6

−2.23

0.000039

CCL8

Chemokine (c-c motif) ligand 8

−5.05

0.045934

IL1R1

Interleukin-1 receptor, type 1

−2.95

0.037396

IL1RN

Interleukin-1 receptor antagonist

−4.99

0.011812

NAMPT

Nicotinamide phosphoribosyltransferase

−1.92

0.016427

PF4

Platelet factor 4

−2.21

0.035662

  1. aFreeze-dried Carica papaya leaf juice; dengue virus infected AG129 mice were given 1000 mg/kg BW
  2. bThe fold regulation cut off is 1.5
  3. cGene expression are considered to show significant differential expression at a P value of < 0.05